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Chemistry · Glossary

What is Acid–base extraction?

Also known as: acid--base extraction

Definition 35.5 University Chemistry — Year 2 · Chapter 35 — Lab Techniques II: Synthesis and Analysis in Practice

An acid–base extraction separates acidic, basic and neutral organic compounds dissolved in an organic solvent by washing the solution with aqueous acids or bases, which convert one class of compounds into ions that pass into the water.

Acid–base separation of four compounds (). The organic layer (left column) loses one class at each wash; each aqueous extract (right) gives back its compound when the pH is reversed.
Acid–base separation of four compounds (Proposition 35.6). The organic layer (left column) loses one class at each wash; each aqueous extract (right) gives back its compound when the pH is reversed.
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