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Chemistry · Glossary

What is Molecular recognition?

Also known as: complementarity · preorganisation

Definition 25.3 University Chemistry — Year 3 · Chapter 25 — Supramolecular Chemistry

Molecular recognition is the selective binding of a guest by a host. It relies on complementarity, a match of size, shape and binding sites between host and guest, and is strengthened by preorganisation, a host whose binding sites are already held in the geometry of the complex before binding.

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