What is Validation?

Trueness is the closeness of the mean of a large number of results to the true value; their difference is the bias. Precision is the closeness of independent results to each other, expressed as a standard deviation: repeatability under the same conditions (same operator, instrument, laboratory, short time), reproducibility under changed conditions (different laboratories). Method validation is the set of experiments that establish, for a method, its trueness, precision, linearity and range, and its limits of detection and quantification.