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Chemistry · Glossary

What is Hard and soft acids?

Also known as: hard acid · soft acid · hard and soft acid--base principle

Definition 24.2 University Chemistry — Year 3 · Chapter 24 — Bioinorganic Chemistry

A hard acid is a small, highly charged, weakly polarisable Lewis acid (HX+\ce{H+}, MgX2+\ce{Mg^2+}, CaX2+\ce{Ca^2+}, FeX3+\ce{Fe^3+}); a soft acid is a large, polarisable one of low charge (CuX+\ce{Cu+}, AgX+\ce{Ag+}, HgX2+\ce{Hg^2+}, CdX2+\ce{Cd^2+}). The hard and soft acid–base principle states that hard acids bind preferably to hard bases (oxygen donors, fluoride) and soft acids to soft bases (sulfur donors, iodide).

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