Biology · Glossary

What is Codon and the genetic code?

Also known as: codon · genetic code

Definition 14.5 High School Biology · Chapter 14 — From Gene to Protein

The mRNA is read in consecutive groups of three nucleotides, the codons, from a defined starting point. The genetic code is the correspondence between the 64 possible codons and the 20 amino acids: 61 codons specify an amino acid, three (UAA, UAG, UGA) are stop signals ending the chain, and AUG, which specifies methionine, also serves as the start codon. The code is degenerate — most amino acids have several codons — and universal: the same table serves every known organism, with rare minor variants.

second letter
firstUCAGthird
UUUU PheUCU SerUAU TyrUGU CysU
UUC PheUCC SerUAC TyrUGC CysC
UUA LeuUCA SerUAA stopUGA stopA
UUG LeuUCG SerUAG stopUGG TrpG
CCUU LeuCCU ProCAU HisCGU ArgU
CUC LeuCCC ProCAC HisCGC ArgC
CUA LeuCCA ProCAA GlnCGA ArgA
CUG LeuCCG ProCAG GlnCGG ArgG
AAUU IleACU ThrAAU AsnAGU SerU
AUC IleACC ThrAAC AsnAGC SerC
AUA IleACA ThrAAA LysAGA ArgA
AUG MetACG ThrAAG LysAGG ArgG
GGUU ValGCU AlaGAU AspGGU GlyU
GUC ValGCC AlaGAC AspGGC GlyC
GUA ValGCA AlaGAA GluGGA GlyA
GUG ValGCG AlaGAG GluGGG GlyG
The genetic code, read on the mRNA. Each codon is found by its first letter (row), second letter (column) and third letter (line within the block). AUG is both methionine and the start signal; three codons are stops.
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