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Chemistry · Glossary

What is Claisen condensation?

Also known as: beta-keto ester

Definition 25.14 University Chemistry — Year 2 · Chapter 25 — Enols, Enolates and the Aldol Reaction

In a Claisen condensation, the enolate of an ester attacks the carbonyl of another ester molecule in an acyl substitution, giving a β\beta-keto ester and releasing an alkoxide. Its intramolecular version, the Dieckmann cyclisation, gives a cyclic β\beta-keto ester.

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